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- Normobaric oxygenation (NBO) is a novel approach to elevate the pressure of oxygen in the ischemic penumbra, it can also exert neuro-protective effects against chronic ischemia and other hypoxic diseases, and moreover, it is considered as safe and convenient, especially in ICH setting clinically; unlike hyperbaric oxygenation (HBO), NBO required no special device and has no contraindication as HBO does, and moreover, NBO can be performed in bedside with lower cost.
Sep 23, 2021 · Normobaric oxygen treatment at a concentration of 40% was found safe in animal and human studies without evidence of pulmonary oxygen toxicity or neurological abnormalities 23.
- Yehudit Bloch, R. H. Belmaker, Pesach Shvartzman, Pnina Romem, Arkady Bolotin, Yuly Bersudsky, Abed ...
- 2021
Jun 15, 2015 · This review considers the evidence for the effectiveness and safety of oxygen administration for migraine or cluster headache. It includes both the use of oxygen at high percentage of normal atmospheric pressure (normobaric oxygen therapy (NBOT)) and the use of 100% oxygen at pressures above one atmosphere (HBOT).
Sep 23, 2021 · Normobaric oxygen treatment at a concentration of 40% was found safe in animal and human studies without evidence of pulmonary oxygen toxicity or neurological abnormalities 23. On the other hand, the use of maximally high inspired oxygen percentage (100% O 2 ) was found to reduce cerebral blood flow 24 .
- Yehudit Bloch, R. H. Belmaker, Pesach Shvartzman, Pnina Romem, Arkady Bolotin, Yuly Bersudsky, Abed ...
- 10.1038/s41598-021-98245-9
- 2021
- Sci Rep. 2021; 11: 18911.
These are critical questions, since theoretically normobaric oxygen has several distinct advantages over hyperbaric therapy; normobaric therapy is safer and has very few, if any, contraindications in the vast majority of patients, it is readily available and much less costly.
- Reza Dana
- 2012
Oct 15, 2018 · Normobaric oxygen (NBO) is a routine adjuvant oxygenation intervention supplied by nasal cannula or facemask (such as Venturi mask) with one atmosphere pressure (1 ATA =101.325 kPa). 7 Evidence available shows that NBO may be a safe, convenient and promising therapeutic strategy for multiorgan protection, which has garnered increasing attention ...
- Jiayue Ding, Da Zhou, Cheng Liu, Liqun Pan, Jingyuan Ya, Yuchuan Ding, Yuchuan Ding, Xunming Ji, Ran...
- 2019
Jan 26, 2021 · Normobaric oxygenation (NBO) was reported attenuating ischemic brain injury. Herein, we aimed to explore the safety and efficacy of NBO on rescuing the damaged brain tissues secondary to acute ICH, especially those in the perihematoma area being threatened by ischemia and hypoxia.
Currently, oxygen therapy is becoming more accepted. Normobaric hyperoxia (NBHO) is considered safe and easy to use regardless of location, including in an ambulance, emergency room, or operating room, which is valuable for the acute phase of "time is brain" [ 4 , 5 ].
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