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- The exact cause of AERD is not known but it is not an allergic response. There is no proof to show that it's genetic or inherited. The disease is not caused by taking aspirin or NSAIDs, but AERD sinus or asthma symptoms get worse when taking these medicines.
www.mayoclinic.org/diseases-conditions/asthma/in-depth/aerd/art-20482797
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Mar 28, 2023 · The exact cause of AERD is not known but it is not an allergic response. There is no proof to show that it's genetic or inherited. The disease is not caused by taking aspirin or NSAIDs, but AERD sinus or asthma symptoms get worse when taking these medicines.
Is AERD genetic? AERD does not run in families. You did not inherit it from your parents and your children have no increased chance of developing the disease because you have it. There may be some genetic factors involved in the development of the disease, but it is not passed on from one generation to the next.
AERD is not a genetic or inherited disorder. People with AERD/Samter’s Triad often have high levels of cells called eosinophils in their blood and in their sinuses, which may lead to chronic inflammation of the airways.
Genetic disorders occur when a mutation affects your genes or chromosomes. Some disorders cause symptoms at birth, while others develop over time. Genetic testing can help you learn more about the likelihood of experiencing a genetic disorder.
No strong genetic predisposition to or basis of AERD has been found, and familial AERD is rare. In addition, there is no relationship between past use of NSAIDs and onset of AERD [2]
Jul 22, 2023 · Previous studies have determined that up to 6% of patients with aspirin-exacerbated respiratory disease (AERD) have family history of AERD, indicating a possible link with genetic polymorphisms. However, whole exome sequencing (WES) studies of such associations are currently lacking.
Oct 16, 2023 · We suggest, in line with Stevens and Cahill, 2 that AERD is a chronic respiratory disease characterized by asthma and rhinosinusitis with recurrent nasal polyps and intolerance to nonspecific COX inhibitors, regardless of the cellular inflammatory endotype of asthma (Table I). 3 Chronic rhinosinusitis with nasal polyps in AERD is difficult to tr...
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related to: Is are a genetic disease?Learn What Happens When You Have Chronic GVHD, Leading to Inflammation & Fibrosis. Watch Videos of People Discussing the Challenges of Living with Chronic GVHD.
