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  1. There is evidence that suggests inbreeding certain animals can have more of a negative impact than a positive one. The two largest populations of koalas in Australia could cease to exist by just one disease, due to them being so so heavily inbred, scientists have warned.

    • Alfie Shaw
    • Search Strategy
    • Study Inclusion Criteria
    • Study Quality Assessment
    • Coding System For The Systematic Map
    • Systematic Map Database

    Scope of search

    The literature search was conducted in two phases. Searches in the first phase were run in November 2010; these interrogated all literature indexed prior to this search date. We subsequently updated these searches on 12thAugust 2013. In this second phase we limited the search to all articles published during or after 2010. Both phases of literature searching used the same search terms, and interrogated the same databases. The following online databases were searched for relevant literature an...

    Search terms

    We used the search strings listed in Table 1 to retrieve articles indexed in the above online databases. Search terms were identified by reference to articles cited in traditional reviews [2,18], consultation with subject experts within the review group and simplified trial searches. Compound search strings were generated by combining each of the search strings. The sensitivity of the search strings was tested and refined using 15 ‘control’ papers, selected to cover a range of publication dat...

    Relevant subject

    Studies that assessed the outcomes of inbreeding in natural populations of wild species, at any location globally, and experimental individuals and progeny derived from these were included. Natural populations were defined as those that have been founded by natural/spontaneous colonisation, or naturalised or (re-) introduced populations that persist in the absence of human intervention. No inter-specific studies or studies on hybrid swarms were considered. Studies involving species that were...

    Types of intervention/exposure

    The intervention/exposure were “inbred crosses” resulting from: 1. Experimental or observed natural crosses among related individuals within the study population; 2. Natural or experimentally induced self-fertilisation; 3. Experimental crosses between individuals separated by known distances within the population; 4. Experimental or observed natural crosses among apparently random individuals within the study population.

    Types of comparator

    The comparator takes the form of observed or experimental non-inbred crosses. The comparator and its corresponding exposure/intervention cross were defined according to the information presented in the study. The comparator is the offspring stemming from relatively less related parent individuals, and included crosses between randomly selected or unrelated individuals within the population or crosses between individuals separated by larger physical distances within the population. In addition...

    The quality of studies was assessed at the full text level. The procedure for quality assessment was based on that proposed in the original protocol (Table 3). However, four design features (relating to comparator and exposure crosses, study populations, selection of individuals crossed, and status of the study population) were excluded from the li...

    Articles were described and categorised using a combination of keywords or continuous values generated from the information reported in the studies and expert knowledge in the review team (Additional file 2). Articles were considered to contain multiple studies in cases where inbreeding outcomes were measured in more than one species, or where the ...

    Following coding of relevant articles and assessment of quality (Table 3) we created a searchable systematic map (database) to describe the scope of available data on inbreeding responses and to identify knowledge gaps. This database can be used for further analysis of the data, as it enables articles to be searched and ordered according to keyword...

  2. Dec 20, 2023 · In conclusion, inbreeding is a complex genetic issue with significant implications for the future of genetic research. By studying the consequences of inbreeding and developing strategies to manage its effects, researchers can work towards preserving the genetic diversity and health of populations for years to come.

  3. Aug 18, 2024 · In humans, it's associated with consanguinity and incest, in which close relatives have sexual relationships and children. Inbreeding violates modern social norms but is fairly common in animals and plants. While inbreeding generally is considered negative, it also offers some positive effects.

    • Anne Marie Helmenstine, Ph.D.
  4. Apr 21, 2024 · Understanding the implications of interbreeding is essential in the field of biology and evolution. Interbreeding, also known as hybridization, occurs when individuals from two distinct species within the same genus reproduce. This can result in hybrid offspring that exhibit a combination of genetic characteristics from both parental species.

  5. May 1, 2002 · Whether inbreeding affects the demography and persistence of natural populations has been questioned. However, new pedigree data from field populations and molecular and analytical tools for tracing patterns of relationship and inbreeding have now enhanced our ability to detect inbreeding depression within and among wild populations.

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  7. en.wikipedia.org › wiki › InbreedingInbreeding - Wikipedia

    Each individual will have similar immune systems, as immune systems are genetically based. When a species becomes endangered, the population may fall below a minimum whereby the forced interbreeding between the remaining animals will result in extinction. Natural breedings include inbreeding by necessity, and most animals only migrate when ...