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  1. Apr 24, 2019 · In 1955, an American doctor named Harry Eagle made a surprising discovery about cancer cells growing in a dish: They required ridiculous amounts of glutamine. Without this chemical, the cells would stop growing and eventually die, despite having all the other known requirements for life.

  2. Jun 17, 2021 · In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new computer-based technique showing that human cancer cells grown in culture dishes are the least genetically similar to their human sources.

  3. Jun 18, 2021 · Summary: In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, scientists report they have developed a new computer-based...

  4. When cultured on a substrate in a dish, cancer cells typically flatten and move in a slow, seemingly random fashion by pulling themselves along by their leading edges. They also form strong attachments, called focal adhesions, to the floor of the dish.

  5. Jun 1, 2018 · We introduce the ways different types of cancer cells were reprogrammed and how their characteristics changed after reprogramming (Figure 2). We discuss the benefits and obstacles in applying induced pluripotent cancer cells (iPCCs) to both basic and pre-clinical research.

    • Mo Liu, Jian Tu, Jian Tu, Julian A Gingold, Celine Shuet Lin Kong, Dung-Fang Lee
    • Am J Cancer Res. 2018; 8(6): 944-954.
    • 2018
    • 2018
  6. Jun 18, 2021 · In a bid to find or refine laboratory research models for cancer that better compare with what happens in living people, Johns Hopkins Medicine scientists report they have developed a new...

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  8. The investigators say their work adds to evidence that cancer cell lines grown in the laboratory have less parity with their human source because of the complex differences between a...

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