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  1. Jan 1, 2014 · Bone modeling is defined as either the formation of bone by osteoblasts or resorption of bone by osteoclasts on a given surface. This contrasts with bone remodeling (discussed below), in which osteoblast and osteoclast activity occur sequentially in a coupled manner on a given bone surface ( Table 4.1 ).

  2. Jul 18, 2022 · The bone marrow stroma contains self-renewing, multipotent progenitors that can give rise to osteoblasts, thus ensuring a reservoir of bone-forming cells for bone growth, modeling and remodeling ...

  3. Bone modeling adapts bone shape to variable mechanical demands during growth and aging through cellular events that determine bone resorption and formation on opposing cortical and cancellous surfaces. This implies the existence of a modeling drift, which moves a bone structural unit over time in the direction defined by growth patterns, and ...

  4. Mar 17, 2023 · Bones are not inert structures within the human body; they continue to change over the course of a lifespan. This process of skeletal change is known as bone remodeling, which both protects the structural integrity of the skeletal system and metabolically contributes to the body's balance of calcium and phosphorus. Remodeling entails the resorption of old or damaged bone, followed by the ...

    • Paul Rowe, Adam Koller, Sandeep Sharma
    • 2023/03/17
    • 2019
  5. Bone modeling adapts structure to loading by changing bone size and shape and removes damage and so maintains bone strength. Remodeling is initiated by damage producing osteocyte apoptosis, which signals the location of damage via the osteocyte-canalicular system to endosteal lining cells that form the canopy of a bone remodeling compartment ...

    • Ego Seeman
    • 2009
  6. Jun 1, 2004 · Bone modeling is a mechanically mediated adaptive process for changing a bone’s size, shape, or position. Site specific, anabolic and catabolic modeling events are manifestations of overload hypertrophy and disuse atrophy, respectively. Catabolic bone modeling at the periodontal ligament (PDL) surface is the rate-limiting step in tooth ...

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  8. Bone is a dynamic tissue that undergoes continual adaption during vertebrate life to attain and preserve skeletal size, shape, and structural integrity and to regulate mineral homeostasis. Two processes, remodeling and modeling, underpin development and maintenance of the skeletal system.

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