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  1. Jan 1, 2014 · Bone modeling is defined as either the formation of bone by osteoblasts or resorption of bone by osteoclasts on a given surface. This contrasts with bone remodeling (discussed below), in which osteoblast and osteoclast activity occur sequentially in a coupled manner on a given bone surface (Table 4.1).

  2. Bone repair, or healing, is the process in which a bone repairs itself following a bone fracture. You can see an X-ray of bone fracture in Figure 14.5.4 14.5. 4. In this fracture, the humerus in the upper arm has been completely broken through its shaft.

  3. Bone tissue is removed by osteoclasts, and then new bone tissue is formed by osteoblasts. Both processes utilize cytokine (TGF-β, IGF) signalling.In osteology, bone remodeling or bone metabolism is a lifelong process where mature bone tissue is removed from the skeleton (a process called bone resorption) and new bone tissue is formed (a process called ossification or new bone formation).

  4. Mar 17, 2023 · Bones are not inert structures within the human body; they continue to change over the course of a lifespan. This process of skeletal change is known as bone remodeling, which both protects the structural integrity of the skeletal system and metabolically contributes to the body's balance of calcium and phosphorus. Remodeling entails the resorption of old or damaged bone, followed by the ...

    • Paul Rowe, Adam Koller, Sandeep Sharma
    • 2023/03/17
    • 2019
  5. The bone marrow stroma contains self-renewing, multipotent progenitors that can give rise to osteoblasts, thus ensuring a reservoir of bone-forming cells for bone growth, modeling and remodeling. 273 Anatomically, the BM stroma is part of the skeleton and is present in all bones except auditory ossicles, which therefore do not undergo remodeling. 274 The definition of skeletal stem cells and ...

  6. Jul 18, 2022 · The bone marrow stroma contains self-renewing, multipotent progenitors that can give rise to osteoblasts, thus ensuring a reservoir of bone-forming cells for bone growth, modeling and remodeling ...

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  8. Bone modeling adapts structure to loading by changing bone size and shape and removes damage and so maintains bone strength. Remodeling is initiated by damage producing osteocyte apoptosis, which signals the location of damage via the osteocyte-canalicular system to endosteal lining cells that form the canopy of a bone remodeling compartment ...

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