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1. • • Game theory can provide insights into the stability of cooperation among cells in a tumour and into the design of potentially evolution-proof therapies that disrupt this cooperation.
     www.nature.com/articles/s41568-018-0083-7

     Cooperation among cancer cells: applying game theory to cancer

2. People also ask

   Can game theory improve cancer treatment?

   • Optimizing Cancer Treatment Using Game Theory: A Review Physicians can exploit the advantages inherent in the asymmetries of the cancer treatment game, and likely improve outcomes, by adopting more dynamic treatment protocols that integrate eco-evolutionary dynamics and modulate therapy accordingly.

   Optimizing Cancer Treatment Using Game Theory: A Review

   pubmed.ncbi.nlm.nih.gov/30098166/

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   Is cancer treatment a game theoretic contest?

   • Observations: We investigate cancer treatment as a game theoretic contest between the physician's therapy and the cancer cells' resistance strategies. This game has 2 critical asymmetries: (1) Only the physician can play rationally.

   Optimizing Cancer Treatment Using Game Theory: A Review

   pubmed.ncbi.nlm.nih.gov/30098166/

   See all results for this question

   Is cancer therapy a Stackelberg game?

   • Second, cancer therapy is a Stackelberg game in which the physician can both influence overall tumor burden and potentially steer the evolutionary trajectory of the cancer cells toward outcomes more favorable to the patient. In terms of the evolution of resistance, the physician can anticipate while the cancer cells can only react.

   Optimizing Cancer Treatment Using Game Theory - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6947530/

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   Can evolutionary game theory model cancer evolution?

   • Many studies have used evolutionary game theory (EGT) to model cancer evolution and in each of them the focus is the interactions between different cancer phenotypes. Tomlinson and Bodmer [ 11] were the first ones to use EGT to model cancer. In their work the interactions between cancer cells in the context of angiogenesis is considered.

   Cancer immunoediting: A game theoretical approach - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC8203245/

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   What is the cancer therapy predator-prey game?

   • The cancer therapy predator-prey game differs from those in nature in ways that limit the physician: he or she does not gain a fitness advantage from killing cancer cells and his or her strategies are constrained by costs, ethics, and treatment toxic effects.

   Optimizing Cancer Treatment Using Game Theory - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6947530/

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   What is game theory & how does it work?

   • Contests such as between the physician and cancer cells can be framed mathematically using game theory. Developed by Von Neumann and Morgenstern, 1 Nash, 2 and others, 3 game theory describes the strategies (choices), payoffs (consequences), and dynamical interactions involving both individuals and populations.

   Optimizing Cancer Treatment Using Game Theory - PMC

   www.ncbi.nlm.nih.gov/pmc/articles/PMC6947530/

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3. www.ncbi.nlm.nih.gov › pmc › articlesOptimizing Cancer Treatment Using Game Theory - PMC

   www.ncbi.nlm.nih.gov › pmc › articles

   Jan 1, 2019 · We investigate cancer treatment as a game theoretic contest between the physician’s therapy and the cancer cells’ resistance strategies. This game has 2 critical asymmetries: (1) Only the physician can play rationally.

   • Optimizing Cancer Treatment Using Game Theory: A Review

     Physicians can exploit the advantages inherent in the...

   • Cooperation among cancer cells: applying game theory to cancer

     A full understanding of cooperation among the cells of a...

   • Cancer immunoediting: A game theoretical approach - PMC

     Introduction. Understanding how the immune system affects...

4. pubmed.ncbi.nlm.nih.gov › 30098166Optimizing Cancer Treatment Using Game Theory: A Review

   pubmed.ncbi.nlm.nih.gov › 30098166

   Jan 1, 2019 · Physicians can exploit the advantages inherent in the asymmetries of the cancer treatment game, and likely improve outcomes, by adopting more dynamic treatment protocols that integrate eco-evolutionary dynamics and modulate therapy accordingly.

   • Author: Katerina Stanková, Katerina Stanková, Joel S Brown, William S Dalton, Robert A Gatenby

   • Publish Year: 2019

5. Videos

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     Cancers are in an evolutionary battle with treatments – evolutionary game theory could tip the advantage to medicine

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     What Game Theory Reveals About Life, The Universe, and Everything

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6. www.nature.com › articles › s41568/018/0083-7Cooperation among cancer cells: applying game theory to cancer

   www.nature.com › articles › s41568/018/0083-7

   Nov 23, 2018 · A full understanding of cooperation among the cells of a tumour requires methods and concepts from evolutionary game theory, which has been used successfully in other areas of biology to...

   • Author: Marco Archetti, Kenneth J. Pienta

   • Publish Year: 2019

7. news.cornell.edu › stories › 2020Game theory suggests more efficient cancer therapy

   news.cornell.edu › stories › 2020

   • Cached

   Apr 23, 2020 · Cornell mathematicians are using game theory to model how the competition between cancer cells can be leveraged, so cancer treatment – which takes a toll on the patient’s body – might be administered more sparingly, with maximized effect.

8. www.ncbi.nlm.nih.gov › pmc › articlesCooperation among cancer cells: applying game theory to cancer

   www.ncbi.nlm.nih.gov › pmc › articles

   A full understanding of cooperation among the cells of a tumour requires methods and concepts from evolutionary game theory, which has been used successfully in other areas of biology to understand similar problems but has been underutilized in cancer research.

   • Author: Marco Archetti, Kenneth J. Pienta
   • DOI: 10.1038/s41568-018-0083-7

   • Publish Year: 2019
   • Published: 2019/02

9. theconversation.com › cancers-are-in-anCancers are in an evolutionary battle with treatments ...

   theconversation.com › cancers-are-in-an

   • Cached

   Nov 16, 2021 · Evolutionary game theory can help researchers and oncologists more effectively predict how cancers will respond to different treatments and potentially control the evolutionary trajectory of...

10. www.ncbi.nlm.nih.gov › pmc › articlesCancer immunoediting: A game theoretical approach - PMC

    www.ncbi.nlm.nih.gov › pmc › articles

    May 28, 2021 · Introduction. Understanding how the immune system affects cancer progression is one of the most important topics in cancer immunology. The immune system plays an important role in cancer evolution. Cancer cells are originated by mutations in tumor suppressor genes, DNA repair genes, and oncogenes in normal cells [1].