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   What is the best treatment for severe acute pain?

   • Severe acute pain is typically treated with potent opioids. At each step, adjuvant medications directed at the underlying condition can be used. Newer medications with dual actions (e.g., tapentadol) are also an option. There is little evidence that one opioid is superior for pain control, but there are some pharmacologic differences among opioids.

   Pharmacologic Therapy for Acute Pain | AAFP

   www.aafp.org/pubs/afp/issues/2013/0601/p766.html

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   What medications are used to treat acute pain in adults?

   • Table 1 summarizes medications used to treat acute pain in adults. 6 – 16 The WHO pain relief ladder recommends a nonopioid such as acetaminophen or a nonsteroidal anti-inflammatory drug (NSAID) for the initial management of pain.

   Pharmacologic Therapy for Acute Pain | AAFP

   www.aafp.org/pubs/afp/issues/2013/0601/p766.html

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   What is Pharmacologic management of acute pain?

   • Pharmacologic management of acute pain should be tailored for each patient, including a review of treatment expectations and a plan for the time course of prescriptions. Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line treatment options for most patients with acute mild to moderate pain.

   Pharmacologic Therapy for Acute Pain - AAFP

   www.aafp.org/pubs/afp/issues/2021/0700/p63.html

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   What is the optimal strategy for acute pain control?

   • The optimal strategy for acute pain control consists of multimodal therapy to increase efficacy, reduce side effects of therapy, and minimize the need for opioids. This topic will discuss the rationale for and concepts of multimodal analgesia and creation of an individualized strategy for analgesia, primarily in the hospital.

   Approach to the management of acute pain in adults - UpToDate

   www.uptodate.com/contents/approach-to-the-management-of-acute-pain-in-adults

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   Are opioids effective for acute pain?

   • Additionally, access and care options may vary. 1, 8 Therefore, a treatment that is effective for one acute pain condition and patient in a particular setting may not be effective in others. Opioids, traditionally considered the most potent analgesics, are frequently used for acute pain.

   Treatments for Acute Pain: A Systematic Review

   effectivehealthcare.ahrq.gov/products/treatments-acute-pain/protocol

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2. www.aafp.org › pubs › afpPharmacologic Therapy for Acute Pain - AAFP

   www.aafp.org › pubs › afp

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   Acetaminophen and nonsteroidal anti-inflammatory drugs (NSAIDs) are first-line treatment options for most patients with acute mild to moderate pain. Topical NSAIDs are recommended for...

3. www.uptodate.com › contents › approach-to-theApproach to the management of acute pain in adults - UpToDate

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   Aug 21, 2024 · The goals of acute pain management are to relieve suffering, facilitate function, enhance recovery, and satisfy patients. After surgery, additional goals are to achieve early postoperative mobilization and reduce length of hospital stay.

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5. effectivehealthcare.ahrq.gov › products › treatmentsTreatments for Acute Pain: A Systematic Review

   effectivehealthcare.ahrq.gov › products › treatments

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   • I. Background and Objectives For The Systematic Review
   • II. The Key Questions
   • III. Methods
   • IV. References
   • VI. Technical Experts
   • VII. Peer Reviewers
   • VIII. EPC Team Disclosures
   • IX. Role of The Funder
   • X. Registration
   • Appendix 1. Medline Search Strategies

   Pain is nearly universal, contributing substantially to morbidity, mortality, disability, and health care system burdens.1,2 Acute pain has been defined as "the physiologic response and experience to noxious stimuli that can become pathologic, is normally sudden in onset, time limited, and motivates behaviors to avoid actual or potential tissue inj...

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   Each Key Question (KQ) for this review focuses on a specific acute pain condition. The conditions and related subquestions are listed below: KQ1:Acute back pain (including back pain with radiculopathy) KQ2:Acute neck pain (including neck pain with radiculopathy) KQ3:Musculoskeletal pain not otherwise included in KQ1 or KQ2 (including fractures) KQ4...

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   Criteria for Inclusion/Exclusion of Studies in the Review

   The criteria for inclusion and exclusion of studies will be based on the Key Questions and are described in the previous PICOTS section. Key Questions on opioid and nonopioid therapy focus on comparative effectiveness because the effectiveness of analgesics for treating acute pain are well established. Key Questions on nonopioid therapies include comparisons against sham, waitlist, usual care, attention control, and no therapy due to greater uncertainty regarding their role in management of a...

   Searching for the Evidence: Literature Search Strategies for Identification of Relevant Studies to Answer the Key Questions

   Publication Date Range:Electronic searches for evidence were conducted in August 2019, and were conducted back to the inception of each database. Electronic searches will be updated while the draft report is out for public review to identify new publications. Literature identified during the updated search will be assessed by following the same process of dual review as all other studies considered for inclusion in the report. If any pertinent new literature is identified for inclusion in the...

   Data Abstraction and Data Management

   After studies are selected for inclusion, data will be abstracted into categories that include but are not limited to: study design, year, setting, country, sample size, eligibility criteria, population and clinical characteristics, intervention characteristics, and results relevant to each Key Question as outlined in the previous PICOTS section. Information that will be abstracted that is relevant for assessing applicability will include the number of patients randomized relative to the numb...

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   Institute of Medicine. Relieving Pain in America: A Blueprint for Transforming Prevention, Care, Education, and Research. Washington, D.C.: The National Academies Press; 2011.

   Henschke N, Kamper SJ, Maher CG. The epidemiology and economic consequences of pain. Mayo Clin Proc. 2015 Jan;90(1):139-47. doi: 10.1016/j.mayocp.2014.09.010. PMID: 25572198.

   Tighe P, Buckenmaier CC, 3rd, Boezaart AP, et al. Acute pain medicine in the United States: a status report. Pain Med. 2015 Sep;16(9):1806-26. doi: 10.1111/pme.12760. PMID: 26535424.

   Kent ML, Tighe PJ, Belfer I, et al. The ACTTION-APS-AAPM Pain Taxonomy (AAAPT) multidimensional approach to classifying acute pain conditions. Pain Med. 2017 May 1;18(5):947-58. doi: 10.1093/pm/pnx...

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   Technical Experts constitute a multi-disciplinary group of clinical, content, and methodological experts who provide input in defining populations, interventions, comparisons, or outcomes and identify particular studies or databases to search. They are selected to provide broad expertise and perspectives specific to the topic under development. Div...

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   Peer reviewers are invited to provide written comments on the draft report based on their clinical, content, or methodological expertise. The EPC considers all peer review comments on the draft report in preparation of the final report. Peer reviewers do not participate in writing or editing of the final report or other products. The final report d...

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   EPC core team members must disclose any financial conflicts of interest greater than $1,000 and any other relevant business or professional conflicts of interest. Related financial conflicts of interest that cumulatively total greater than $1,000 will usually disqualify EPC core team investigators.

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   This project was funded under Contract No. HHSA290201500009I from the Agency for Healthcare Research and Quality, U.S. Department of Health and Human Services. The AHRQ Task Order Officer reviewed contract deliverables for adherence to contract requirements and quality. The authors of this report are responsible for its content. Statements in the r...

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   This protocol will be registered in the international prospective register of systematic reviews (PROSPERO).

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   Treatment effectiveness and harms

   1. Pain/ 2. Acute Pain/ 3. Pain Management/ 4. (acute adj3 pain).ti,ab,kf. 5. exp back pain/ or exp musculoskeletal pain/ or neck pain/ or exp neuralgia/ or exp Facial Pain/ or exp Nephrolithiasis/ or exp Anemia, Sickle Cell/ or Pain, Postoperative/ 6. (back or spine or spinal or radicular or neck or musculoskeletal or fracture* or neuropathic or neuralgia or neuropathy or sciatica or "dental pain" or "ondotogenic pain" or "kidney stone*" or urolithiasis or nephrolithiasis or "sickle cell" or...

   Risk prediction and mitigation

   1. Pain/ 2. Acute Pain/ 3. Pain Management/ 4. (acute adj3 pain).ti,ab,kf. 5. exp back pain/ or exp musculoskeletal pain/ or neck pain/ or exp neuralgia/ or exp Facial Pain/ or exp Nephrolithiasis/ or exp Anemia, Sickle Cell/ or Pain, Postoperative/ 6. (back or spine or spinal or radicular or neck or musculoskeletal or fracture* or neuropathic or neuralgia or neuropathy or sciatica or "dental pain" or "ondotogenic pain" or "kidney stone*" or urolithiasis or nephrolithiasis or "sickle cell" or...

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6. pmc.ncbi.nlm.nih.gov › articles › PMC6179627A Review of Management of Acute Pain - PMC - PubMed Central (PMC)

   pmc.ncbi.nlm.nih.gov › articles › PMC6179627

   Acute pain is a complex process involving activation of nociceptors, chemical mediators and inflammation. Medications can be used to target each of the key elements within the pain pathway and eliminate or reduce the sensation of pain.

7. www.ncbi.nlm.nih.gov › books › NBK566500Treatments for Acute Pain: A Systematic Review [Internet].

   www.ncbi.nlm.nih.gov › books › NBK566500

   The key decisional dilemma in acute pain management involves selection of interventions to provide adequate pain relief, in order to improve quality of life, improve function, and facilitate recovery, while minimizing adverse effects and avoiding overprescribing of opioids. 8 Evidence also suggests that adequate acute pain treatment may mitigate...

   • Published: 2020/12

8. www.iasp-pain.org › resources › topicsAcute Pain - International Association for the Study of Pain ...

   www.iasp-pain.org › resources › topics

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   cuts and infections. burns. pulled or strained muscle. sprains of body part. Diagnosis and Tests. Your medical doctor will likely ask you about your symptoms, the intensity and location of pain, and the history of your injury, surgery, or illness. Young patients may be asked to rate their pain intensity using the faces of pain scale.

9. www.aafp.org › pubs › afpPharmacologic Therapy for Acute Pain | AAFP

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   Jun 1, 2013 · The first-line pharmacologic agent for the symptomatic treatment of mild to moderate pain is acetaminophen or a nonsteroidal anti-inflammatory drug (NSAID).