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Jun 4, 2024 · There are four distinct phases of the growth curve: lag, exponential (log), stationary, and death. The initial phase is the lag phase where bacteria are metabolically active but not dividing. The exponential or log phase is a time of exponential growth.
- Regina Bailey
Mar 28, 2024 · The curve typically consists of four distinct phases: lag phase, log phase (exponential growth phase), stationary phase, and death phase. These phases reflect the changes in the number, size, and mass of bacterial cells during their growth cycle.
- Stages of the Bacterial Growth Curve. Knowing the difference between the lag, log, stationary, and death phases of a cell growth curve may sound like biology basics but applying that knowledge in active cell culture is a sign of a more fundamental understanding of microbiological processes.
- Lag Phase. This initial cell growth phase is generally characterized by metabolic activity but not growth. The cells utilize media to synthesize the small molecules necessary for replication.
- Log (Exponential Growth) Phase. Once cells enter the exponential growth or log phase, it’s all about the numbers. This is when cells divide by binary fission and the doubling of each generation creates the exponential growth for which the phase is named.
- Stationary Phase. As environmental conditions change and become the limiting factor in growth, cells slow reproduction and enter a stationary phase. In this stage cells are technically still reproducing but it is less than before and roughly equal to the amount of cell death.
Feb 17, 2021 · Death phase. The last phase of the bacterial growth curve is ‘ death phase ‘ or decline phase. It is marked by a decline in the number of viable bacteria. During this phase, the total count of bacteria may remain constant but the viable count decreases.
If incubation continues after the population reaches stationary phase, a death phase follows, in which the viable cell population declines. During the death phase, the number of viable cells decreases geometrically (exponentially), essentially the reverse of growth during the log phase.
In autecological studies, the growth of bacteria (or other microorganisms, as protozoa, microalgae or yeasts) in batch culture can be modeled with four different phases: lag phase (A), log phase or exponential phase (B), stationary phase (C), and death phase (D).
Finally the bacterial growth reaches its death phase, in which the death of cells in the population exceeds the formation of new cells. At 96 hours, Bacillis subtillis has reached this phase, as evidenced by its shriveling appearance.
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