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Aug 14, 2023 · Epidemiology of fever of unknown origin (FUO) varies based on etiology of fever, age group, geography, environmental exposure, and immune/HIV status. In developing countries, an infectious etiology of FUO is most prevalent whereas, in developed countries, FUO is likely due to non-infectious inflammatory disease.
- Ilona Brown, Nancy A. Finnigan
- 2023/08/14
- 2021
Fever of unknown origin (FUO) was originally defined by Petersdorf and Beeson as an illness of more than 3 weeks’ duration, with fever greater than 38.3 °C (101 °F) on several occasions, the cause of which is uncertain after 1 week of in-hospital investigations.
Fever of unknown origin (FUO) was first defined by Petersdorf and Beeson in 1961, who defined FUO as body temperature above 38.3°C (101°F) on three or more occasions and a duration of illness of at least three weeks, in which no diagnosis was made after one week of hospital admission. 1 In the following years this definition was modified.
Jul 9, 2024 · Fever of unknown origin (FUO) is body temperature ≥ 38.3° C (≥ 101° F) rectally that does not result from transient and self-limited illness, rapidly fatal illness, or disorders with clear-cut localizing symptoms or signs or with abnormalities on common tests such as chest radiograph, urinalysis, or blood cultures.
- Larry M. Bush
Feb 2, 2022 · In 1961, Petersdorf and Beeson defined fever of unknown origin (FUO) as a temperature of 38.3°C or higher for at least 3 weeks without a diagnosis, despite 1 week of inpatient...
Fever of unknown origin (FUO) is a serious challenge for physicians. The aim of the present study was to consider epidemiology and dynamics of FUO in countries with different economic development.
Aug 14, 2023 · The revised definition proposed by Durack and Street in 1991 divided cases into four distinct subclasses: classic FUO, nosocomial FUO, neutropenic FUO, and HIV-related FUO. A comprehensive history and physical examination can aid in diagnosis and direct diagnostic testing.
