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The paradox of aerobic life, or the 'Oxygen Paradox', is that higher eukaryotic aerobic organisms cannot exist without oxygen, yet oxygen is inherently dangerous to their existence. This 'dark side' of oxygen relates directly to the fact that each oxygen atom has one unpaired electron in its outer valence shell, and molecular oxygen has two unpaired electrons.
- Kelvin J.A. Davies
- 1995
Dec 21, 2017 · Basic aspects of the Oxygen Paradox, the French Paradox, and ageing. Cellular homeostasis is constantly challenged by reactive oxygen and nitrogen species which are either generated endogenously during cellular metabolism (e.g., by mitochondria, NADPH oxidases, and cytochrome P450 reductases) or originate from exogenous sources including drugs, xenobiotics metals, and radiation.
- Joanna M. S. Davies, Josiane Cillard, Bertrand Friguet, Bertrand Friguet, Enrique Cadenas, Jean Cade...
- 2017
The author suggested that this ‘oxygen paradox’ was due to a fall in arterial pressure occurring during oxygen breathing. In this study Latham’s findings have been extended by measuring cerebral blood flow velocity, to investigate changes in cerebral blood flow in this situation and their relationship to changes in arterial pressure and arterial P CO2 .
Jun 13, 2021 · This is the oxygen paradox: oxygen is vital to live, but too much of it can be damaging. I guess it shouldn’t be all that surprising if we look more closely at nature. Life itself is a balance ...
eliminates oxygen (CO 2) properly almost entirely (98%) [1]. Unfortunately, the rest is at the origin of some “hyper-reactive” species called FR (is oxidated derivatives of the electron deficit, unstable oxygen molecule, that cause dysfunctions of all body cells). The volume of oxygen contained by a single inspiration produces a billion FR.
Apr 1, 2016 · Helmut's Oxidative Stress concept is, of course, a complex outcome of a much more simple phenomenon for which I coined the term, “The Oxygen Paradox” [5].Simply stated, the Oxygen Paradox proposes that although Oxygen is essential for aerobic beings, it is also inherently dangerous to the very same lifeforms; in other words, it is very difficult to live without Oxygen, but it is also very ...
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Nov 1, 1995 · The paradox of aerobic life, or the 'Oxygen Paradox', is that higher eukaryotic aerobic organisms cannot exist without oxygen, yet oxygen is inherently dangerous to their existence. This 'dark side' of oxygen relates directly to the fact that each oxygen atom has one unpaired electron in its outer valence shell, and molecular oxygen has two unpaired electrons. Thus atomic oxygen is a free ...
