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  1. Jun 4, 2008 · Cochrane was certainly not the first to question the effectiveness of medical therapies. This prompts the question of what made his book so popular. Cochrane's book was unique because it used an amalgamation of studies to show that the problem of evidence plagued not just one aspect of medicine but was pervasive.

    • Hriday M. Shah, Kevin C. Chung
    • 10.1097/PRS.0b013e3181b03928
    • 2009
    • 2009/09
  2. Physician. Archibald Leman Cochrane CBE (12 January 1909 – 18 June 1988) was a Scottish physician noted for his book, Effectiveness and Efficiency: Random Reflections on Health Services, which advocated the use of randomized controlled trials (RCTs) to improve clinical trials and medical interventions.

  3. In 1972, Archie Cochrane's book Effectiveness and Efficiency drew attention to the need to obtain better evidence to inform the development of health services, and emphasized the important role of evidence derived from randomized controlled trials (Reference Cochrane 23). One consequence of this was that, encouraged by Cochrane himself, one of his readers (I. C.) began to assemble a collection ...

    • Mark Starr, Iain Chalmers, Mike Clarke, Andrew D. Oxman
    • 2009
  4. Archibald L. (Archie) Cochrane was born in 1909 into a wealthy Scottish family, from which he inherited the advantage of a private income and the disadvantage of porphyria. Though a brilliant student, his medical training was interrupted by a lengthy psychoanalysis in Europe, and by service in a field ambulance unit in the Spanish Civil War. Eventually Cochrane qualified in medicine in 1938 ...

  5. tempt was made to prepare either of the books, all of the systematic reviews on which they were based should have been completed, with structured reports prepared, and held in electronic form.” (16). Although the books had proved popular, the publisher— Oxford University Press—found the electronic publication

    • Mark Starr, Iain Chalmers, Mike Clarke, Andrew D. Oxman
    • 2009
  6. The thoughts of Cochrane (1909–1988), more known as Archie Cochrane, deserve to be treasured also by the next generations. His name has become famous worldwide thanks to the Cochrane Collaboration and before it, thanks to the publication of his book Effectiveness and efficiency. Random reflections on health services 1—of which we remember its 50th anniversary this year and was properly ...

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  8. The Cochrane Collaboration and its eponym, Archie Cochrane, have become symbols of this development, and Cochrane's book Effectiveness and Efficiency from 1972 is often referred to as the first sketch of what was to become EBM. In this article, we claim that this construction of EBM's historical roots is based on a selective reading of Cochrane's text.

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