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  1. The lateral plate mesoderm (LPM) forms the progenitor cells that constitute the heart and cardiovascular system, blood, kidneys, smooth muscle lineage and limb skeleton in the developing vertebrate embryo.

  2. Cells from the lateral plate mesoderm and the myotome migrate to the limb field and proliferate to create the limb bud. The lateral plate cells produce the cartilaginous and skeletal portions of the limb while the myotome cells produce the muscle components.

  3. The lateral plate mesoderm. The two layers of the lateral plate mesoderm enclose the intra-embryonic coelom. The mesodermal cells of the lateral plate arrange themselves as thin layers, which become the serous membranes of the body: the pleura, pericardium and peritoneum.

  4. On either side of the intermediate mesoderm resides the lateral plate mesoderm. Each plate splits horizontally into the dorsal somatic (parietal) mesoderm, which underlies the ectoderm, and the ventral splanchnic (visceral) mesoderm, which overlies the endoderm.

    • Scott F Gilbert
    • 2000
    • 2000
  5. Aug 14, 2023 · Overview. The musculoskeletal system develops from three sources: the paraxial mesoderm. the parietal layer of the lateral plate mesoderm. the neural crest cells. The development of bone and muscle begins at the fourth gestational week, when the paraxial mesoderm differentiates into somites; the latter gives rise to sclerotomes and dermomyotomes.

    • Danny Ly
    • Medical Content Validation
  6. There are three distinct lineages that generate the skeleton. The somites generate the axial skeleton, the lateral plate mesoderm generates the limb skeleton, and the cranial neural crest gives rise to the branchial arch and craniofacial bones and cartilage.

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  8. Aug 13, 2020 · Skeletal tissues originate from three types of cell populations: the paraxial mesoderm, lateral plate mesoderm, and neural crest. The paraxial mesoderm gives rise to the sclerotome mainly...

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