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Heart development, also known as cardiogenesis, refers to the prenatal development of the heart. This begins with the formation of two endocardial tubes which merge to form the tubular heart, also called the primitive heart tube. The heart is the first functional organ in vertebrate embryos. The tubular heart quickly differentiates into the ...
The human heart is the first functional organ to develop. It begins beating and pumping blood around day 21 or 22, a mere three weeks after fertilization. This emphasizes the critical nature of the heart in distributing blood through the vessels and the vital exchange of nutrients, oxygen, and wastes both to and from the developing baby.
- Lindsay M. Biga, Sierra Dawson, Amy Harwell, Robin Hopkins, Joel Kaufmann, Mike LeMaster, Philip Mat...
- 2019
The heart begins to develop near the head of the embryo in a region known as the cardiogenic area. Following chemical signals called factors from the underlying endoderm (another of the three primary germ layers), the cardiogenic area begins to form two strands called the cardiogenic cords (Figure \(\PageIndex{1}\)).
- Atrial
- Ventricular
- Outflow Tract
The septation of the primitive atrium involves the formation of two septa and three ‘holes’. Firstly, the septum primumforms and extends down towards the fused endocardial cushions to split the atrium into two. The ostium primum is a hole present before the septum primum completes fusion with endocardial cushions. Before the ostium primum is closed...
The interventricular septumof the ventricles has two components; one muscular and one membranous. The muscular portionforms much of the septum and grows up from the floor of the ventricles towards the fused endocardial cushions, but a small gap, the primary interventricular foramen, remains. This gap is filled by the membranous portion of the inter...
Endocardial cushionsalso appear within the truncus arteriosus which grow towards each other. As they grow towards each other they twist around each other and form a spiral septum, dividing the outflow tract into left and right sides.
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4 days ago · The best place for students to start is the Heart Tutorial. In human embryos the heart begins to beat at about 22-23 days, with blood flow beginning in the 4th week. The heart is therefore one of the earliest differentiating and functioning organs. The heart begins very early in mesoderm within the trilaminar embryonic disc.
Aug 3, 2023 · In human embryos, the heart begins to beat at about 22-23 days, with blood flow beginning in the 4th week. It begins very early in mesoderm within the trilaminar embryonic disc. The heart forms initially in the embryonic disc as a simple paired tube inside the forming pericardial cavity, which when the disc folds, get carried into the correct anatomical position in the chest cavity.
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Aug 14, 2023 · The first system to develop due to the growing embryo's ever-increasing metabolic demands is the cardiovascular system. Initially, simple diffusion of necessary nutrients is sufficient but eventually becomes inadequate to supply oxygen and nutrients. Cardiac development is a complicated interplay of molecular communication, ensuring the proper formation of structures and spatial configuration ...
