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  1. U.S. Route 50 (US 50) runs east–west across the southern part of the state of Ohio, passing through Cincinnati, Chillicothe, and Athens. It is mainly a two-lane road except for the easternmost and westernmost parts. Near Athens it runs concurrently with State Route 32 (SR 32), a four-lane divided highway known as Corridor D, and from ...

  2. Nov 4, 2022 · U.S. Route 50 is a 3,200-mile road that spans 11 states and showcases some of America’s most beautiful scenery -- especially in Ohio. This route winds its way through the entire southern portion of Ohio, showing off some of the Buckeye State's best rural scenery and most charming small towns. The roughly 200-mile stretch of Route 50 through ...

  3. Another split was located between Athens, Ohio and Ellenboro, West Virginia from the late 1920s to the mid-1930s, when US 50 went back to its original southern route; that U.S. Route 50N is now Ohio State Route 550 and part of West Virginia Route 16. [19]

  4. After bisecting Missouri from Kansas City to St. Louis, US-50 crosses the Mississippi River into a much older and more settled landscape, through the agricultural heartlands of Illinois, Indiana, and Ohio. After climbing into the Appalachian backwoods of West Virginia, US-50 emerges suddenly into the wealth and power of downtown Washington DC ...

  5. Stretching across 11 states and showcasing some of America’s best scenery, US Route 50 is a 3,200-mile road everyone in America has likely traveled at least once. It winds its way through the southern portion of Ohio, showing off some of the state’s best rural scenery, riverfront cities and small towns. If you’ve yet to travel this road ...

  6. US 50 is Main Street through town, a quaint small town with many old buildings. Paint Creek runs west of town. Chillicothe was the first and third Capital of Ohio. Tecumseha, named after the great Shawnee Chief, is now a most enduring and extravagant outdoor drama, presented to thousands of visitors nightly in the summer at the beautiful ...

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  8. U.S. Route 50 runs east–west across the southern part of the U.S. state of Ohio, passing through Cincinnati, Chillicothe, and Athens. It is mainly a two-lane road except for the easternmost part. Near Athens it becomes part of State Route 32, a four-lane divided highway known as Corridor D, and from Reedsville to the Ohio/West Virginia border ...

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