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Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.
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Endochondral ossification is responsible for development of most bones including long and short bones, [4] the bones of the axial (ribs and vertebrae) and the appendicular skeleton (e.g. upper and lower limbs), [5] the bones of the skull base (including the ethmoid and sphenoid bones) [6] and the medial end of the clavicle. [7]
The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the long bones form via endochondral ossification.
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Oct 30, 2023 · Endochondral ossification occurs in the long bones around the 6th embryonic week. It involves the formation of hyaline cartilage precursors from aggregated mesenchymal cells , and their subsequent systematic replacement by bone to form the growing skeleton.
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May 13, 2022 · The flat bones of the face, most of the cranial bones, and a good deal of the clavicles (collarbones) are formed via intramembranous ossification, while bones at the base of the skull and the long bones form via endochondral ossification.
Sep 25, 2024 · In endochondral ossification, bone develops by replacing hyaline cartilage. Activity in the epiphyseal plate enables bones to grow in length. Modeling allows bones to grow in diameter.
Jul 30, 2022 · Endochondral Ossification. In endochondral ossification, bone develops by replacing hyaline cartilage. Cartilage does not become bone. Instead, cartilage serves as a template to be completely replaced by new bone. Endochondral ossification takes much longer than intramembranous ossification.
