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Sep 9, 2024 · Using data from the Million Veteran Program, researchers performed a genome-wide association study (GWAS) to identify genetic variations, called “loci,” associated with each of the “Big Five” personality traits: extraversion, openness, agreeableness, neuroticism, and conscientiousness. The researchers then combined these data with ...
Sep 12, 2024 · Personality GWAS meta-analysis and genetic correlations among the five personality traits. Credit: Nature Human Behaviour (2024). DOI: 10.1038/s41562-024-01951-3
We identified six genetic loci, including five novel loci 2,3, significantly associated with personality traits in a meta-analysis of genome-wide association studies (N=123,132–260,861). Of these genome-wide significant loci, extraversion was associated with variants in WSCD2 and near PCDH15 , and neuroticism with variants on chromosome 8p23.1 and in L3MBTL2 .
The summary statistics for the Big Five personality measures is outlined in Table 1. Bivariate correlations between the five personality traits ranged from r =0.09 to 0.41. Sex was significantly associated with all personality traits, except openness. Genetic study (that is, chip effects) was not significantly associated with personality measures.
Dec 5, 2016 · We identified six genetic loci, including five novel loci2,3, significantly associated with personality traits in a meta-analysis of genome-wide association studies (N = 123,132–260,861).
- Min-Tzu Lo, David A. Hinds, Joyce Y. Tung, Carol Franz, Chun-Chieh Fan, Yunpeng Wang, Yunpeng Wang, ...
- 2017
Sep 16, 2024 · Using data from the Million Veteran Program, researchers performed a genome-wide association study (GWAS) to identify genetic variations, called “loci,” associated with each of the “Big Five” personality traits: extraversion, openness, agreeableness, neuroticism, and conscientiousness. The researchers then combined these data with ...
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Oct 10, 2024 · Your DNA has long been known to play a role in shaping your personality. Now, researchers at Yale School of Medicine (YSM) have taken another step in determining exactly how by identifying a number of new genetic sites associated with specific personality traits. They published their findings in Nature Human Behavior on August 12.
