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Dec 8, 2021 · Yeast has been an essential tool to our society since the beginning of time. Beer, bread, and wine all use yeast due to their ability to undergo fermentation. 1 Not only does yeast contribute to creating yummy food, but it also plays an important role in biomedical research. Many scientists, including some at Penn State College of Medicine ...
- Humans and Yeast
- Yeast and Cancer
- Expedited Experiments with Yeast
What makes yeast such a useful model organism? An important feature of yeasts (especially Saccharomyces cerevisiae - a.k.a. S. cerevisiae) is that their cells, like ours, are eukaryotic – meaning they have a nucleus containing DNA packaged into chromosomes. And although it may seem like yeast and humans have very little in common, at least 20 perce...
Over the last several decades, researchers have been tirelessly interrogating all of the mutations that cause cancer in humans. Dr. Leeland Hartwell, a biologist and 2001 Nobel Laureate, was one of the first scientists to discover some of the mutations involved in cancer. Since then, many of the mutations found so far are in genes involved in some ...
What would happen if scientists were able to expedite their research by several orders of magnitude. What if multiple expertiments could be run at the same time, with data delivered almost instantaneously? How much more quickly could they target new drugs and therapies to treat humanity's most deadly diseases? Fenologica's platform quickly performs...
Jan 4, 2024 · The history of yeast Saccharomyces cerevisiae, aka brewer’s or baker’s yeast, is intertwined with our own. Initially domesticated 8,000 years ago to provide sustenance to our ancestors, for the past 150 years, yeast has served as a model research subject and a platform for technology. In this review, we highlight many ways in which yeast has served to catalyze the fields of functional ...
Sep 3, 2021 · Methods: A literature search was conducted investigating general yeast characteristics, genetics and physiology, as well as modern applications in biomedical research as model organisms. Results: Yeasts have many traits that make them especially favorable in research: they can easily be cultivated in laboratory conditions where their metabolism may be altered by tweaking the growth medium ...
- Dusan Pesic
- 2021
May 1, 2005 · Yeast cell-based assays in which the biological function of specific human proteins that do not have a yeast functional counterpart are studied are designated ‘humanized yeast systems’. Examples that demonstrate the use of humanized yeast assays for the study of human disease are those focused on neurological disorders such as Huntington's disease, which is correlated with expansion of ...
- Willem H. Mager, Joris Winderickx
- 2005
Today, the use of yeast is undergoing a "rebirth" in both fundamental and applied research. Indeed, advances in yeast technology have paved the way for a variety of new genome-wide screening approaches. Experimental strategies using yeast aim to unravel disease-related molecular events and to discover novel medicinal compounds.
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Dec 2, 2022 · Yeast is a workhorse for the production of vaccines due to expression of different forms of antigens that can be scalable with reasonable cost. Among several yeast species, Pichia pastoris is considered one of the most promising options for heterologous protein production in vaccine development [ 8 ].
